mercredi 29 avril 2015
mardi 28 avril 2015
lundi 27 avril 2015
Consuming Lentinula edodes (Shiitake) Mushrooms Daily Improves Human Immunity: A Randomized Dietary Intervention in Healthy Young Adults
Xiaoshuang Dai, Joy M. Stanilka, Cheryl A. Rowe, Elizabethe A. Esteves, Carmelo Nieves Jr., Samuel J. Spaiser, Mary C. Christman, Bobbi Langkamp-Henken and Susan S. Percival
Department of Food Science and Human Nutrition, University of Florida, Gainesville, Floridab Department of Nutrition, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, MG, BRAZILc MCC Statistical Consulting, Gainesville, Florida
Published online: 11 Apr 2015
Background: Mushrooms are widely cited for their medicinal qualities, yet very few human intervention studies have been done using contemporary guidelines.
Objective: The aim of this study was to determine whether consumption of whole, dried Lentinula edodes (shiitake) mushrooms could improve human immune function. Primary objectives were to ascertain whether L. edodesconsumption would improve γδ-T cell proliferation and activation responses, quantify a dose response, and elicit cytokine secretion patterns. Secondary objectives included determining changes in natural killer T (NK-T) cell proliferation and activation, secretory immunoglobulin A (sIgA) in saliva, and C-reactive protein (CRP) in serum.
Design: Fifty-two healthy males and females, aged 21–41 years, participated in a 4-week parallel group study, consuming either 5 or 10 g of mushrooms daily. Each subject had blood drawn before and after 4 weeks of daily L. edodes consumption. Saliva and serum were also collected. Peripheral blood mononuclear cells were cultured in autologous serum for 24 hours or 6 days, stained, and examined by flow cytometry.
Results: Eating L. edodes for 4 weeks resulted in increased ex vivo proliferation of γδ-T (60% more, p < 0.0001) and NK-T (2-fold more, p < 0.0001) cells. Both cell types also demonstrated a greater ability to express activation receptors, suggesting that consuming mushrooms improved cell effector function. The increase in sIgA implied improved gut immunity. The reduction in CRP suggested lower inflammation. The pattern of cytokines secreted before and after mushroom consumption was significantly different; consumption resulted in increased interleukin (IL)-4, IL-10, tumor necrosis factor (TNF)-α, and IL-1α levels, a decreased macrophage inflammatory protein-1α/chemokine C-C ligand 3 (MIP-1α/CCL3) level, and no change to IL-6, IL-1β, MIP-1β, IL-17 and interferon (IFN)-γ levels.
Conclusions: Regular L. edodesconsumption resulted in improved immunity, as seen by improved cell proliferation and activation and increased sIgA production. The changes observed in cytokine and serum CRP levels suggest that these improvements occurred under conditions that were less inflammatory than those that existed before consumption.
dimanche 26 avril 2015
samedi 25 avril 2015
mercredi 22 avril 2015
lundi 20 avril 2015
dimanche 19 avril 2015
samedi 18 avril 2015
vendredi 17 avril 2015
jeudi 16 avril 2015
mercredi 15 avril 2015
mardi 14 avril 2015
lundi 13 avril 2015
dimanche 12 avril 2015
vendredi 10 avril 2015
jeudi 9 avril 2015
mercredi 8 avril 2015
Oleocanthal concentration in EVOO is highly variable, ranging from as little as 0.2 mg/kg to as high as 498 mg/kg (Gomez-Rico et al., 2006). Such variation in oleocanthal concentration amongst differing EVOOs may be due to multiple factors that have the capacity to modify the concentration of this compound (Carrasco-Pancorbo et al., 2005). These factors include: method of phenolic extraction and quantification, geographic region of olive growth, olive tree cultivar, agricultural techniques applied to cultivate olives, olive maturity, processing of the olives to oil, storage of oil, and domestic heat application to oil.
mardi 7 avril 2015
"Les herbicides ne sont pas très toxiques pour les bactéries testées, à savoir E. coli et Salmonella enterica serovar Typhimurium : la bactérie reste vivante, mais elle active des pompes protéiques pour se libérer des toxines. Ce mécanisme de défense peut favoriser l’apparition de résistances croisées. « L’exposition à ces pesticides rend les pathogènes plus forts. »
L’utilisation excessive et inappropriée des antibiotiques compromet l’efficacité à long terme des thérapies qui utilisent les antibiotiques. L’émergence de la résistance aux antibiotiques est le résultat de l’utilisation des antibiotiques. La résistance aux antibiotiques induite par les pesticides pourrait aussi affecter les abeilles étant donné que de nombreuses ruches sont maintenant traitées avec des antibiotiques."
vendredi 3 avril 2015
|Bacon, fried 5 min no added oil||91,577|
jeudi 2 avril 2015
CONCLUSIONS: It is concluded that leucine supplementation was found to exert beneficial effects on body weight, body mass index, and lean body mass in older persons in those subjects already prone to sarcopenia, but not muscle strength. However, due to the heterogeneity between the trials included in this systematic review, further studies adopting a homogenous design with respect to participant characteristics duration as well as the kind and amount of daily supplement in use are required.
Cancer patients are disabled by sarcopenia. It seems that EPA can help.
On pourrait faire un contre menu:
Agneau catalan fermier et sa ratatouille
Salade de fruits rouges ou patisserie au choix
mercredi 1 avril 2015
It appears that the supplement food industry had tried with success to bypass evidence based medicine and grew on unproven basis. The backlash of the public didn't occur but industrial leaders of the field should think twice before doing business as usual.