So dietary cholesterol is not a nutrient of concern of overconsumption? Actually? Sure it is new?

That dietary cholesterol is not important

for man would be predicted

from the fact that the biliary output of

cholesterol from the human liver is from

10 to 20 times as much as the daily

amount of cholesterol in any diet of

natural foods. Repeated careful dietary

surveys on large numbers of persons in

whom blood cholesterol was measured

consistently fail to disclose a relationship

between the cholesterol in the diet

and in the serum.19-2' Infants and children,

as well as adults, show this lack of

dependence of serum content upon the

exogenous supply of cholesterol,22 but

this does not mean that the diet is unimportant

in regard to the blood cholesterol.

Controlled experiments on men

clearly show that serum cholesterol

changes in direct relation to a change

in the total amount of fat in the

diet.7 23-25 Both animal and vegetable

fats show this effect and the addition or

removal of cholesterol in the diet does

not change the result. The blood

cholesterol may fall, however, if the diet

is almost exclusively pure fat and is free

of carbohydrate;26 this highly artificial

experiment would seem to have no relevance

to natural situations.

A Keys

1953

They were so slow to understand that it could discredit other advices...